MALARIA VACCINE: PROSPECTS AND CHALLENGES

Abdulwasiu Oladele  Hassan; Oluwafisayomi Victoria  Oso; Emmanuel Ifeanyi Obeagu; Abolaji Tolulope  Adeyemo

Abdulwasiu Oladele Hassan Department of Medical Laboratory Science, Achievers University, Owo, Ondo State, Nigeria
Oluwafisayomi Victoria Oso Department of Medical Laboratory Science, Achievers University, Owo, Ondo State, Nigeria
Emmanuel Ifeanyi Obeagu Department of Medical Laboratory Science, Imo State University, Owerri, Imo State, Nigeria
Abolaji Tolulope Adeyemo Department of Medical Microbiology and Parasitology, College of Health Sciences, Osun State University, Osogbo, Nigeria.

Keywords: malaria, vaccine, prospects, challenges

Abstract

Malaria is a life-threatening disease caused by the plasmodium genus, malaria can cause a range of symptoms and life –threatening complications so an early diagnosis is crucial. In many parts of the world, the parasites have developed resistance to a number of antimalarial drugs. Interventions control the spread malaria has been embarked on over the years, such interventions include the use of herbs, and insecticide treated nets, covering or oiling the surface of open water source, treatment with artemisinin-based combination therapies. The most recent intervention is the malaria vaccine just approved by the World Health Organization known as RTS, S(ASO1). This vaccine confers immunity to children between 2-18 months. Before the approval of the malaria vaccine various clinical trials had been embarked on to demonstrate the variable safety and immunogenicity of the vaccine. In this review, we summarised the latest research progress in combating the spread of malaria, life cycle of malaria, pathogenesis of malaria, the prospects and challenges of the newly released malaria vaccine.

MALARIA VACCINE: PROSPECTS AND CHALLENGES

Abstract

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